Gestophil 400 mg Vaginal Suppositories 15'sGestophil Vaginal suppositories consist mainly of progesterone, one of the steroidal female hormones that regulate the function of the female reproductive system. Gestophil suppositories restore the natural hormonal balance in the body. Vaginal suppositories relieve the symptoms associated with premenstrual syndrome and the symptoms of the menstrual cycle, as the concentration of the progesterone hormone decreases shortly before the menstrual cycle.